KEY WORDS: Lactuca scariola, Tukhme Kahu, Unani medicine, Sedative. The present review will provide comprehensive information on phytochemical and therapeutic uses with special reference to Unani medicine which will help to tap its unexplored potential with more scientific approach. ![]() The drug exhibits varied pharmacological activities such as sedative, hypnotic, diuretic, deobstruent, antipyretic, anti inflammatory, blood purifier, demulcent, refrigerant, anesthetic and antispasmodic, anti cancer, antibacterial, bronchodilator and vasorelaxant. ![]() The present article explores the Unani classical and published scientific literature to compile the traditional and scientific data comprising pharmacognostic description, pharmacological studies, therapeutic uses, and safety profile of Lactuca scariola to date. It is easily available and cost effective drug which has drawn interest of many researchers and is screened for various bioactive substances. Recently the discovery of active components from the plant and their biological function in disease control has led to active interest in the plant across the globe. ![]() Tukhme ka.hu (Prickly lettuce seed) has traditionally been used for the treatment of headache, insomnia, nervousness, hypertension, palpitation, fever etc. Lactuca scariola Linn (prickly lettuce) is an important drug in Unani system of medicine.
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